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Coronary Intervention > Intervention > Coronary Stent Systems

Orsiro®


In the current edition of the journal Interventional Cardiology BIOTRONIK has published the Orsiro article “Orsiro - The first Hybrid Drug-eluting Stent, Opening Up a New Class of Drug-eluting stent for superior Patient Outcome” written by Michael Tittelbach and Tobias Diener.

Abstract
The Orsiro device is a hybrid drug-eluting stent that represents a new strategy in the treatment of coronary artery stenosis. Orsiro features a hybrid coating of passive and active components: the proBIO passive coating seals the metal surface of the stent and prevents interaction with the surrounding blood and tissue, while the BIOlute active coating contains a highly biocompatible polymer that delivers a -limus drug over 12–14 weeks and degrades gently over one to two years, thereby avoiding increased inflammation. The stent backbone is the PRO-Kinetic Energy platform, which has a double-helix stent design and thin struts, bringing flexibility and ease of deliverability.
Tittelbach, M; Diener, T; Orsiro – The First Hybrid Drug-eluting Stent, Opening Up a New Class of Drug-eluting Stents for Superior Patient Outcomes | Interventional Cardiology, 2011;6(2):142–4

Orsiro Product Description:
Industry's first hybrid drug eluting stent with a bioabsorbable polymer
A unique solution for treating coronary artery stenosis with a hybrid combination of passive and active components:
Passive component: proBIO passive coating encapsulates the stent and eliminates interaction between the metal stent and the surrounding tissue.
Active component: BIOlute® is a bioabsorbable polymer matrix combined with a Limus drug and utilized the advantages of controlled drug release. In the long term, the patient is left with only a proBIO coated stent.

Advanced stent design
The stent platform for Orsiro is PRO-Kinetic Energy, our sixth generation of coronary bare metal stents. The stent material is a cobolt chromium alloy which allows for thinner struts while maintaining optimal radial strength and radiopacity. The thin struts of only 60 µm also result in exceptional flexibility and deliverability of the stent in even the most challenging vessels.

Stent Delivery System: Pantera balloon technology
Thanks to our modern balloon technology deliverability of the stent is effortless and smooth. The Enhanced Force Transmission Shaft (EFT) adds pushability and trackability to this high performing device.

New DES specific crimping
An advanced crimping technique ensures a low crossing profile (0.99 mm/0.039") and secure stent retention without affecting the BIOlute® coating.